CRL-1341: Cutaneous Melanoma

Charles River Laboratories


Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
Not Specified NMRI
Not Specified Not Specified Not Specified Not Specified 9
NMRI Crl:NMRI-Foxn1nu
subcutaneous heterotopic tissue fragment Not Specified 0, 8
NMRI Crl:NMRI-Foxn1nu
Not Specified Not Specified Not Specified Not Specified 26, 5, 9
Model Quality Control
Technique Description Passage
histology high concordance between xenograft passages <5,9,17
Patient
Sex female
Ethnicity caucasian
Derived Model CRL-1341
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age 35
Diagnosis Cutaneous Melanoma
Type metastatic
PDX Mouse CRL-1341
Collection Site lung
Grade ( Classification: )
Stage m1 ( Classification: tnm)
Date Regimen Started Regimen Dose Best Response Duration (Months)
Interleukin-2 NA Not Specified NA
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
Oncotest-111B Engrafted Tumor Passage 9 mutation View data Illumina WES Not Available
E6R_005a01 Engrafted Tumor Passage 5 expression View data Affymetrix HGU133plus2 Not Available
MEXF_1341-6216 Engrafted Tumor Passage 8 copy number alteration View data Affymetrix SNP6.0 Not Available
MEXF_1341-6216 Engrafted Tumor Passage 8 mutation View data Illumina WES Not Available
Oncotest-R0081 Engrafted Tumor Passage 26 expression View data ILLUMINA Not Available
Oncotest-R0081 Engrafted Tumor Passage 26 mutation View data ILLUMINA Not Available
Oncotest-R0081 Engrafted Tumor Passage 26 mutation View data RNA sequencing Not Available
MEXF_1341-6216 Engrafted Tumor Passage 9 copy number alteration View data Affymetrix SNP6.0 Not Available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: