CRL-2085: Colon Cancer

Charles River Laboratories


Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
Not Specified NMRI
Not Specified Not Specified Not Specified Not Specified 3
NMRI Crl:NMRI-Foxn1nu
subcutaneous heterotopic tissue fragment Not Specified 0, 2
NMRI Crl:NMRI-Foxn1nu
Not Specified Not Specified Not Specified Not Specified 3, 5, 6
Model Quality Control
Technique Description Passage
histology high concordance between xenograft passages <5,8,12
Patient
Sex male
Ethnicity caucasian
Derived Model CRL-2085
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age 74
Diagnosis Colon Cancer
Type metastatic
PDX Mouse CRL-2085
Collection Site liver
Grade g3
Stage t3n3m1 ( Classification: tnm)
Date Regimen Started Regimen Dose Best Response Duration (Months)
Cetuximab and Fluorouracil and Irinotecan and Leucovorin NA / NA / NA / NA Not Specified NA / NA / NA / NA
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
A1955-012rh Engrafted Tumor Passage 2 copy number alteration View data Affymetrix SNP6.0 Not Available
A1955-012rh Engrafted Tumor Passage 2 mutation View data Illumina WES Not Available
CRL-R0233 Engrafted Tumor Passage 5 mutation View data RNA sequencing Not Available
CRL-R0233 Engrafted Tumor Passage 5 expression View data ILLUMINA Not Available
CRL-R0233 Engrafted Tumor Passage 5 mutation View data ILLUMINA Not Available
Oncotest-1034 Engrafted Tumor Passage 3 mutation View data Illumina WES Not Available
A1955-012rh Engrafted Tumor Passage 3 copy number alteration View data Affymetrix SNP6.0 Not Available
A1742-25 Engrafted Tumor Passage 6 expression View data Affymetrix HGU133plus2 Not Available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: