CRL-449: Breast Cancer

Charles River Laboratories


Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
Not Specified NMRI
Not Specified Not Specified Not Specified Not Specified 20
NMRI Crl:NMRI-Foxn1nu
subcutaneous heterotopic tissue fragment Not Specified 0, 19, 8
NMRI Crl:NMRI-Foxn1nu
Not Specified Not Specified Not Specified Not Specified 13, 20
Model Quality Control
Technique Description Passage
histology high concordance between xenograft passages <5,11,33
Patient
Sex female
Ethnicity caucasian
Derived Model CRL-449
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age 53
Diagnosis Breast Cancer
Type primary
PDX Mouse CRL-449
Collection Site breast
Grade g3
Stage t3n1m0 ( Classification: tnm)
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
MAXF_449-8651 Engrafted Tumor Passage 20 copy number alteration View data Affymetrix SNP6.0 Not Available
Oncotest-105B Engrafted Tumor Passage 20 mutation View data Illumina WES Not Available
E6R_028e05 Engrafted Tumor Passage 13 expression View data Affymetrix HGU133plus2 Not Available
449 Engrafted Tumor Passage 8 cytogenetics View data Immunohistochemistry Not Available
MAXF_449-8651 Engrafted Tumor Passage 19 mutation View data Illumina WES Not Available
MAXF_449-8651 Engrafted Tumor Passage 19 expression View data ILLUMINA Not Available
MAXF_449-8651 Engrafted Tumor Passage 19 mutation View data RNA sequencing Not Available
MAXF_449-8651 Engrafted Tumor Passage 19 mutation View data ILLUMINA Not Available
MAXF_449-8651 Engrafted Tumor Passage 19 copy number alteration View data Affymetrix SNP6.0 Not Available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: