CRC0219LM: Colorectal Carcinoma

Candiolo Cancer Institute - Colorectal


Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
subcutis right heterotopic tissue fragment Not Specified 1, 2
Not Specified Not Specified
Not Specified Not Specified Not Specified Not Specified 1, 2
Model Quality Control
Technique Description Passage
fingerprint model validated against patient germline. 0, 1, 2
Patient
Sex male
Ethnicity Not specified
Derived Model CRC0219LM
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age 70
Diagnosis Colorectal Carcinoma
Type metastatic
PDX Mouse CRC0219LM
Collection Site liver
Grade not provided ( Classification: )
Stage 3 ( Classification: )
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
CRC0219LMX0B02201TUMR01R01 Engrafted Tumor Passage 2 mutation Data is not available in the Finder TargetedNGS MUT Not Available
CRC0219LMX0B02201TUMR01R01 Engrafted Tumor Passage 2 expression View data Illumina HT-12 v4 microarray Not Available
CRC0219LMX0B02201TUMR01R01 Engrafted Tumor Passage 2 copy number alteration View data Targeted Next Generation Sequencing Not Available
CRC0219LMX0A02201TUMD04000 Engrafted Tumor Passage 2 mutation View data TargetedNGS MUT Not Available
CRC0219LMX0A01201TUMR01R01 Engrafted Tumor Passage 1 copy number alteration View data whole exome sequencing EGAN00001286068
CRC0219LMX0A01201TUMR01R01 Engrafted Tumor Passage 1 expression View data Illumina HT-12 v4 microarray EGAN00001286068
CRC0219LMX0A01201TUMR01R01 Engrafted Tumor Passage 1 mutation Data is not available in the Finder whole exome sequencing EGAN00001286068
CRC0219LMX0A01201TUMD01000 Engrafted Tumor Passage 1 mutation View data whole exome sequencing Not Available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform:    

Drug Dose Response
Cetuximab 20 mg/Kg Partial Response
Saline 0 mg/Kg Progressive Disease