CRC0516LM: Colorectal Carcinoma

Candiolo Cancer Institute - Colorectal


Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
subcutis right heterotopic tissue fragment Not Specified 1, 2
Not Specified Not Specified
Not Specified Not Specified Not Specified Not Specified 1, 2
NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
Not Specified Not Specified Not Specified Not Specified 3
Model Quality Control
Technique Description Passage
fingerprint model validated against patient germline. 0, 1, 2
Patient
Sex male
Ethnicity Not specified
Derived Model CRC0516LM
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age 65
Diagnosis Colorectal Carcinoma
Type metastatic
PDX Mouse CRC0516LM
Collection Site liver
Grade not provided ( Classification: )
Stage 4 ( Classification: )
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
CRC0516LMX0B02003TUMD05000 Engrafted Tumor Passage 2 copy number alteration View data Targeted Next Generation Sequencing Not Available
CRC0516LMX0B02003TUMD05000 Engrafted Tumor Passage 2 mutation Data is not available in the Finder TargetedNGS MUT Not Available
CRC0516LMX0B01001TUMD05000 Engrafted Tumor Passage 1 mutation Data is not available in the Finder whole exome sequencing EGAN00001286186
CRC0516LMX0B01001TUMD05000 Engrafted Tumor Passage 1 copy number alteration View data whole exome sequencing EGAN00001286186
CRC0516LMX0B02003TUMD05000 Engrafted Tumor Passage 2 mutation View data TargetedNGS MUT Not Available
CRC0516LMX0B03003TUMR01R01 Engrafted Tumor Passage 3 expression View data Illumina HT-12 v4 microarray GSM1986752
CRC0516LMX0B01001TUMD05000 Engrafted Tumor Passage 1 mutation View data whole exome sequencing Not Available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform:    

Drug Dose Response
Cetuximab 20 mg/Kg Partial Response
Saline 0 mg/Kg Progressive Disease