J000106527: Invasive Breast Carcinoma of No Special Type

The Jackson Laboratory

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Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
mammary fat pad orthotopic surgical resection (fragment) Not Specified 1
Model Quality Control
Technique Description Passage
histology, ki67 ihc, cd45 ihc, str analysis the histology of the engrafted tumor retains morphologic features of the primary patient tumor as assessed by a board certified pathologist. ihc for human ki67 validates that the tumor cells are actively dividing and are of human origin. ihc for cd45 and cytokeratin (ae1/ae3) rules out a xenograft-associated lymphocytic tumor. str analysis validates provenance of engrafted tumor. not specified
Patient
Sex female
Ethnicity hispanic
Derived Model J000106527
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age not specified
Diagnosis Invasive Breast Carcinoma of No Special Type
Type primary
PDX Mouse J000106527
Collection Site breast
Grade grade:3 ( Classification: ajcc)
Stage t4 ( Classification: ajcc)
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
BCM-3469 Engrafted Tumor Passage 1 expression View data RNA Seq BAYLOR Not Available
BCM-3469 Engrafted Tumor Passage 1 mutation View data Whole Exome BAYLOR Not Available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: