J000106527: Invasive Breast Carcinoma of No Special Type
The Jackson Laboratory
Related Models |
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PDX model Engraftment | |||||
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Host Strain Name | Site | Type | Material | Material Status | Passage |
NSG
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
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mammary fat pad | orthotopic | surgical resection (fragment) | Not Specified | 1 |
Model Quality Control | ||
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Technique | Description | Passage |
histology, ki67 ihc, cd45 ihc, str analysis | the histology of the engrafted tumor retains morphologic features of the primary patient tumor as assessed by a board certified pathologist. ihc for human ki67 validates that the tumor cells are actively dividing and are of human origin. ihc for cd45 and cytokeratin (ae1/ae3) rules out a xenograft-associated lymphocytic tumor. str analysis validates provenance of engrafted tumor. | not specified |
Patient | |
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Sex | female |
Ethnicity | hispanic |
Derived Model | J000106527 |
Patient Tumor Collection For PDX Model |
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Collection (Current Model) | |
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Age | not specified |
Diagnosis | Invasive Breast Carcinoma of No Special Type |
Type | primary |
PDX Mouse | J000106527 |
Collection Site | breast |
Grade | grade:3 ( Classification: ajcc) |
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Stage | t4 ( Classification: ajcc) |
Sample ID | Sample Type | Engrafted Tumor Passage | Data Type | Data Available | Platform Used | Raw Data |
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BCM-3469 | Engrafted Tumor | Passage 1 | expression | View data | RNA Seq BAYLOR | Not Available |
BCM-3469 | Engrafted Tumor | Passage 1 | mutation | View data | Whole Exome BAYLOR | Not Available |
Sample ID: Histology: Tumor Type: Engrafted Tumor Passage: Platform:
