TM00884: Renal Cell Carcinoma

The Jackson Laboratory


Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
not specified heterotopic surgical resection (fragment) Not Specified 1
NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
Not Specified Not Specified Not Specified Not Specified 0
Model Quality Control
Technique Description Passage
histology, ki67 ihc, cd45 ihc, str analysis the histology of the engrafted tumor retains morphologic features of the primary patient tumor as assessed by a board certified pathologist. ihc for human ki67 validates that the tumor cells are actively dividing and are of human origin. ihc for cd45 and cytokeratin (ae1/ae3) rules out a xenograft-associated lymphocytic tumor. str analysis validates provenance of engrafted tumor. not specified
Patient
Sex female
Ethnicity not hispanic or latino
Derived Model TM00884
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age not specified
Diagnosis Renal Cell Carcinoma
Type metastatic
PDX Mouse TM00884
Collection Site lung
Grade ( Classification: ajcc)
Stage ajcc iv ( Classification: ajcc)
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
LG0937F309P0 Engrafted Tumor Passage 0 copy number alteration View data SNP Not Available
LG0937F309P0 Engrafted Tumor Passage 0 expression View data hu133 Not Available
LG0937F309P0 Engrafted Tumor Passage 0 mutation View data Truseq JAX Not Available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: