Related Models |
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PDX model Engraftment | |||||
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Host Strain Name | Site | Type | Material | Material Status | Passage |
NSG
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
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not specified | heterotopic | surgical resection (fragment) | Not Specified | 1 |
NSG
NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
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Not Specified | Not Specified | Not Specified | Not Specified | 0 |
Model Quality Control | ||
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Technique | Description | Passage |
histology, ki67 ihc, cd45 ihc, str analysis | the histology of the engrafted tumor retains morphologic features of the primary patient tumor as assessed by a board certified pathologist. ihc for human ki67 validates that the tumor cells are actively dividing and are of human origin. ihc for cd45 and cytokeratin (ae1/ae3) rules out a xenograft-associated lymphocytic tumor. str analysis validates provenance of engrafted tumor. | not specified |
Patient | |
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Sex | female |
Ethnicity | not hispanic or latino |
Derived Model | TM00884 |
Patient Tumor Collection For PDX Model |
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Collection (Current Model) | |
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Age | not specified |
Diagnosis | Renal Cell Carcinoma |
Type | metastatic |
PDX Mouse | TM00884 |
Collection Site | lung |
Grade | ( Classification: ajcc) |
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Stage | ajcc iv ( Classification: ajcc) |
Sample ID | Sample Type | Engrafted Tumor Passage | Data Type | Data Available | Platform Used | Raw Data |
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LG0937F309P0 | Engrafted Tumor | Passage 0 | copy number alteration | View data | SNP | Not Available |
LG0937F309P0 | Engrafted Tumor | Passage 0 | expression | View data | hu133 | Not Available |
LG0937F309P0 | Engrafted Tumor | Passage 0 | mutation | View data | Truseq JAX | Not Available |
Sample ID: Histology: Tumor Type: Engrafted Tumor Passage: Platform:
