TM01594: Glioblastoma

The Jackson Laboratory


Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
Not Specified Not Specified Not Specified Not Specified 2
NSG NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ
right flank heterotopic surgical resection (fragment) Not Specified 1
Model Quality Control
Technique Description Passage
validation is pending. validation is pending. not specified
Patient
Sex male
Ethnicity not reported
Derived Model TM01594
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age not specified
Diagnosis Glioblastoma
Type primary
PDX Mouse TM01594
Collection Site brain
Grade grade:4 ( Classification: ajcc)
Stage not specified
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
TM01594F062P2 Engrafted Tumor Passage 2 copy number alteration View data SNP Not Available
TM01594F062P2 Engrafted Tumor Passage 2 expression View data stRNA Seq Not Available
TM01594F062P2 Engrafted Tumor Passage 2 copy number alteration View data SNPTN Not Available
TM01594F062P2 Engrafted Tumor Passage 2 mutation View data CTP Not Available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform:    

Drug Dose Response
Dextrose Monohydrate 5.0ml/kg Progressive Disease
Temozolomide 50.0mg/kg Stable Disease
Bevacizumab 5.0mg/kg Stable Disease
Valproic Acid 400.0mg/kg Progressive Disease
Sirolimus 5.0mg/kg Progressive Disease
Bevacizumab and Sirolimus 5.0mg/kg / 5.0mg/kg Partial Response