519858-162-T: Colon Adenocarcinoma

Patient-Derived Models Repository


Patient
Sex Female
Age at Time of Collection 56
Race / Ethnicity / Not Specified
Patient Tumor
Histology Colon Adenocarcinoma
Primary Tissue Digestive/Gastrointestinal
Collection Site Not Specified
Tumor Type Not Specified
Grade Intermediate grade ( Classification: )
Stage Not Specified
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NOD scid gamma Subcutaneous (flank) Heterotopic Not Specified Not Specified 0, 2, 3, Not Specified
Model Quality Control
Technique Description Passage
Histology Model validated against histological features of same diagnosis All
Human mouse/DNA Model validated against patient tumour or P0 xenograft All
Fingerprinting Model validated against patient tumour or P0 xenograft All
Collection (Other Model)
Age 56
Diagnosis Colon Adenocarcinoma
Type Not Specified
PDX Mouse Not Specified
Collection Site Not Specified
Sex Female
Race / Ethnicity Not specified / Not Specified
Date Regimen Started Regimen Dose Best Response Duration (Months)
2013-03-01 Fluorouracil and Irinotecan and Leucovorin and Ziv-Aflibercept Not Specified Stable Disease 12 Months / 12 Months / 12 Months / 12 Months
2014-03-01 Regorafenib Not Specified Non-evaluable 1 Months
2012-03-01 Bevacizumab and Fluorouracil and Leucovorin Calcium and Oxaliplatin Not Specified Partial Response 2 Months / 2 Months / 2 Months / 2 Months
2012-08-01 Bevacizumab and Fluorouracil and Leucovorin Calcium and Oxaliplatin Not Specified Partial Response 7 Months / 7 Months / 7 Months / 7 Months
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
ORIGINATOR Patient Tumor Passage NA mutation View data NCI cancer gene panel NCI cancer gene panel Not available
T24TK7U91V04 Engrafted Tumor Passage 3 mutation View data NCI cancer gene panel NCI cancer gene panel Not available
T24TK8U95 Engrafted Tumor Passage 2 mutation View data NCI cancer gene panel NCI cancer gene panel Not available
T24TK6UD6V01 Engrafted Tumor Passage 3 mutation View data NCI cancer gene panel NCI cancer gene panel Not available
T24 Engrafted Tumor Passage 0 mutation View data NCI cancer gene panel NCI cancer gene panel Not available
T24TK8U94V07 Engrafted Tumor Passage 3 mutation View data NCI cancer gene panel NCI cancer gene panel Not available
T24TK6UD8 Engrafted Tumor Passage 2 mutation View data NCI cancer gene panel NCI cancer gene panel Not available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: