945468-187-T: Rectal Adenocarcinoma

Patient-Derived Models Repository


Patient
Sex Male
Age at Time of Collection 54
Race / Ethnicity / Not Hispanic or Latino
Patient Tumor
Histology Rectal Adenocarcinoma
Primary Tissue Digestive/Gastrointestinal
Collection Site Not Specified
Tumor Type Metastatic
Grade Intermediate grade ( Classification: )
Stage Not Specified
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NOD scid gamma Subcutaneous (flank) Heterotopic Not Specified Not Specified 0, 1, Not Specified
Model Quality Control
Technique Description Passage
Human mouse/DNA Model validated against patient tumour or P0 xenograft All
Histology Model validated against histological features of same diagnosis All
Fingerprinting Model validated against patient tumour or P0 xenograft All
Collection (Current Model)
Age 54
Diagnosis Rectal Adenocarcinoma
Type Metastatic
PDX Mouse 945468-187-T
Collection Site Not Specified
Sex Male
Race / Ethnicity Not specified / Not Hispanic or Latino
Date Regimen Started Regimen Dose Best Response Duration (Months)
2015-02-01 Capecitabine Not Specified Partial Response 2 Months
2015-06-01 Fluorouracil and Leucovorin Calcium and Oxaliplatin Not Specified Stable Disease 3 Months / 3 Months / 3 Months
Sample ID Sample Type Engrafted Tumor Passage Data Type Data Available Platform Used Raw Data
HAHVT9 Engrafted Tumor Passage 1 mutation View data NCI cancer gene panel NCI cancer gene panel Not available
HAH Engrafted Tumor Passage 0 mutation View data NCI cancer gene panel NCI cancer gene panel Not available
HAHVU5 Engrafted Tumor Passage 1 mutation View data NCI cancer gene panel NCI cancer gene panel Not available
HAHVT8 Engrafted Tumor Passage 1 mutation View data NCI cancer gene panel NCI cancer gene panel Not available

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: