SJOS046149_X2: Childhood Osteosarcoma
St Jude Children's Research Hospital
Related Models | |
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Models | SJOS046149_X1 |
PDX model Engraftment | |||||
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Host Strain Name | Site | Type | Material | Material Status | Passage |
NOD SCID
NOD.Cg-Prkdcscid/J
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bone marrow/intrafemur | orthotopic | dissociated cells | Not Specified | 1 |
Model Quality Control | ||
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Technique | Description | Passage |
ihc | various stains depending on diagnosis, high concordance between xenograft and patient tumor | 1,2 |
rna seq | high concordance between xenograft and patient tumor | 1,2 |
histology | h&e, high concordance between xenograft and patient tumor | 1,2 |
fingerprinting | str analysis between passages to confirm xenografts | 1,2 |
wgs | high concordance between xenograft and patient tumor | 1,2 |
Publications | |
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Title | Orthotopic Patient-derived Xenografts Of Paediatric Solid Tumours. |
Authors | Stewart E, Federico SM, Chen X ... Dyer MA. |
Publication year | 2017 |
Journal | Orthotopic patient-derived xenografts of paediatric solid tumours. |
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Patient | |
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Sex | female |
Ethnicity | not provided |
Derived Model | SJOS046149_X2 SJOS046149_X1 |
Patient Tumor Collection For PDX Model |
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Collection (Other Model) | Collection (Current Model) | |
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Age | 12 | 13 |
Diagnosis | Childhood Osteosarcoma | Childhood Osteosarcoma |
Type | recurrent | recurrent |
PDX Mouse | SJOS046149_X1 | SJOS046149_X2 |
Collection Site | back | lung |
Grade | not specified |
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Stage | not specified |
Sample ID: Histology: Tumor Type: Engrafted Tumor Passage: Platform:
