SJOS046149_X2: Childhood Osteosarcoma

St Jude Children's Research Hospital


Related Models
Models SJOS046149_X1
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NOD SCID NOD.Cg-Prkdcscid/J
bone marrow/intrafemur orthotopic dissociated cells Not Specified 1
Model Quality Control
Technique Description Passage
ihc various stains depending on diagnosis, high concordance between xenograft and patient tumor 1,2
rna seq high concordance between xenograft and patient tumor 1,2
histology h&e, high concordance between xenograft and patient tumor 1,2
fingerprinting str analysis between passages to confirm xenografts 1,2
wgs high concordance between xenograft and patient tumor 1,2
Publications
Title Orthotopic Patient-derived Xenografts Of Paediatric Solid Tumours.
Authors Stewart E, Federico SM, Chen X ... Dyer MA.
Publication year 2017
Journal Orthotopic patient-derived xenografts of paediatric solid tumours.
Patient
Sex female
Ethnicity not provided
Derived Model SJOS046149_X2 SJOS046149_X1
Patient Tumor Collection For PDX Model
Collection (Other Model) Collection (Current Model)
Age 12 13
Diagnosis Childhood Osteosarcoma Childhood Osteosarcoma
Type recurrent recurrent
PDX Mouse SJOS046149_X1 SJOS046149_X2
Collection Site back lung
Grade not specified
Stage not specified

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: