SJRB030317_X1: Childhood Intraocular Retinoblastoma

St Jude Children's Research Hospital


Related Models
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
CB17 SCID B6.Cg-Prkdcscid/SzJ 
intra ocular orthotopic dissociated cells Not Specified 1
Model Quality Control
Technique Description Passage
fingerprinting str analysis between passages to confirm xenografts 1,2
ihc various stains depending on diagnosis, high concordance between xenograft and patient tumor 1,2
wgs high concordance between xenograft, patient tumor and germline 1,2
histology h&e, high concordance between xenograft and patient tumor 1,2
Publications
Title Orthotopic Patient-derived Xenografts Of Paediatric Solid Tumours.
Authors Stewart E, Federico SM, Chen X ... Dyer MA.
Publication year 2017
Journal Orthotopic patient-derived xenografts of paediatric solid tumours.
Patient
Sex male
Ethnicity not provided
Derived Model SJRB030317_X1
Patient Tumor Collection For PDX Model
Collection (Current Model)
Age 20 months
Diagnosis Childhood Intraocular Retinoblastoma
Type primary
PDX Mouse SJRB030317_X1
Collection Site eye
Grade not specified
Stage not specified

Sample ID:     Histology:     Tumor Type: Engrafted Tumor     Passage:     Platform: