BRC0004PR: Invasive Ductal Carcinoma Not Otherwise Specified

TRACE-PDTX platform


Patient
Sex Female
Age at Time of Collection 33
Race / Ethnicity Not Specified
Patient Tumor
Histology Invasive Ductal Carcinoma Not Otherwise Specified
Primary Tissue breast
Collection Site breast
Tumor Type Primary
Grade Grade 3 ( Classification: Nottingham Histology System Score)
Stage T2, N0, M0 ( Classification: TNM staging system)
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NOG interscapular fat pad heterotopic tissue fragment fresh 0,1
NMRI nude interscapular fat pad heterotopic tissue fragment fresh 2,3,4
Model Quality Control
Technique Description Passage
Fingerprinting high concordance between xenograft and patient tumour 0,1
Fingerprinting high concordance between xenograft and patient tumour 2,3,4
Histology high concordance between xenograft and patient tumour 2
Histology high concordance between xenograft and patient tumour 0,1
Collection (Current Model)
Age 33
Diagnosis Invasive Ductal Carcinoma Not Otherwise Specified
Type Primary
PDX Mouse BRC0004PR
Collection Site breast
Sex Female
Race / Ethnicity Not Specified
Date Regimen Started Regimen Dose Best Response Duration (Months)
may/15 Docetaxel 75 mg/m2 Complete Response 2.0
aug/15 Radiotherapy 57,26 Gy in total Complete Response 1.0
may/15 Paclitaxel 80mg/m2 Complete Response 0.5
mar/15 Epirubicin and Cyclophosphamide 90 mg/m2 / 600 mg/m2 Complete Response 2.0 / 2.0