BRC0021PR: Invasive Ductal Carcinoma Not Otherwise Specified

TRACE-PDTX platform

Sex Female
Age at Time of Collection 48
Race / Ethnicity Not Specified
Patient Tumor
Histology Invasive Ductal Carcinoma Not Otherwise Specified
Primary Tissue breast
Collection Site breast
Tumor Type Primary
Grade Grade 3
Stage T2, N1, M0 ( Classification: TNM staging system)
PDX model Engraftment
Host Strain Name Site Type Material Material Status Passage
NMRI nude interscapular fat pad heterotopic tissue fragment fresh 0,1,2,3
Model Quality Control
Technique Description Passage
Fingerprinting high concordance between xenograft and patient tumour 0,1,2,3
Collection (Current Model)
Age 48
Diagnosis Invasive Ductal Carcinoma Not Otherwise Specified
Type Primary
PDX Mouse BRC0021PR
Collection Site breast
Sex Female
Race / Ethnicity Not Specified
Date Regimen Started Regimen Dose Best Response Duration (Months)
apr/16 Denosumab Not specified Progressive Disease 5.0
jun/16 Carboplatin and Gemcitabine Not specified / Not specified Progressive Disease 2.0 / 2.0
feb/16 Capecitabine 500 mg/m2 + 75 mg/m2 + 500 mg/m2 Progressive Disease 4.0
nov/15 Letrozole Nor specified Progressive Disease Not specified
nov/15 Radiotherapy 50 Gy in total Progressive Disease 1.0
jun/15 Paclitaxel 80mg/m2 Progressive Disease 2.0
jun/15 Cyclophosphamide and Epirubicin 600 mg/m2 / 90 mg/m2 Stable Disease 2.5 / 2.5