PDX Resource

The mission of St. Jude Children’s Research Hospital is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment. The Childhood Solid Tumor Network (CSTN) was created to share resources and data to stimulate basic research and speeding translation to the clinic. The CSTN houses hundreds of orthotopic patient derived xenografts (O-PDXs) from more than 20 different types of pediatric solid tumors. Importantly, all patients consented to donate their tumor tissue for xenografting and profiling.
All samples and data are shared free of charge with no obligation to collaborate. The following resources are available:

Stewart, E,* Federico, S,* Chen, X,* et al, Orthotopic patient-derived xenografts of paediatric solid tumours. Nature. 2017 ... Read more

Cancer by System

Data Available